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Our biomarker tests 

OncoDEEP®

Turn deep insights into personalized treatment strategies

 

Cancer type:
Recommended use:
Gene panel:
Sample type:
Turnaround time:

Solid tumors

At diagnosis or disease progression

638 genes

FFPE tissue

<2 weeks

From tumor tissue biopsy to cancer treatment recommendations, OncoDEEP is a comprehensive biomarker test for advanced, metastic solid tumors.

What Is OncoDEEP®?

OncoDEEP® is a comprehensive biomarker test designed to guide treatment of advanced, metastatic solid tumors

When your patients are diagnosed with a rare or highly aggressive cancer, do not respond to the first-line treatment or relapse, OncoDEEP® can provide you with clear clinical guidance. Starting from a small sample of tumor tissue, our test is able to pinpoint the therapeutic vulnerabilities of a tumor and identify appropriate treatment options in a fast turnaround. 

OncoDEEP® is the most comprehensive solution available on the market. It covers a wide range of biomarkers carefully selected for their clinical relevance and offers a unique combination of analyses that proved to maximize the clinical benefits for cancer patients.

In one simple test and in less than two weeks, OncoDEEP® can help you to: 

  • Identify all the approved treatments likely to be effective for your patients;
  • Define which types of therapies your patient is resistant to;
  • Consider appropriate clinical trials;
  • Understand why a treatment stopped working.

Recommended for:

  • • Stage III-IV solid tumors in adults
  • • Glioblastoma in children
  • • CUP cancer

Recommended when:

  • • At diagnosis
  • • First-line treatment not efficient
  • • Recurrence of cancer
  • • Highly aggressive or rare cancers
  • • Primary origin of cancer unknown

Map Out Personalized Treatment Strategies

In less than two weeks, OncoDEEP® generates a comprehensive report that contains deep insights into a patient's tumor as well as therapeutic options, such as chemotherapy, immunotherapy, targeted therapy and hormone therapy; and potential clinical trial options.

Why Choose OncoDEEP®?

Clinical Evidence

We regularly run studies in order to evaluate the clinical impact of our comprehensive biomarker test in real life. Discover our key scientific publications published in peer-reviewed international journals.

FAQs

Comprehensive biomarker testing - also known as comprehensive molecular profiling or cancer genomic testing - is a next-generation sequencing (NGS) approach that uses a single assay to detect relevant cancer biomarkers, alterations in genes that are known to drive cancer growth, as established in guidelines and clinical trials, for therapy guidance. OncoDEEP® goes one step further by integrating tumor-specific biomarker analyses to maximize the clinical benefit for the patients.

Combining different molecular profiling analyses is the key to maximize the clinical benefit for the patients. A study demonstrated the clinical utility of integrating DNA, RNA and proteins in one single molecular profiling test. The trial was led on 1,057 advanced cancer patients in 30 countries on 4 continents that had already experienced treatment failure(s).

The OncoDEEP® comprehensive biomarker test screens for genomic alterations (DNA & RNA), genomic signatures (MSI, TMB, HRD) and protein biomarkers of response to targeted therapies, immunotherapy, hormone therapy and chemotherapy. The technology is robust and accurate, and the genes of the panel were carefully selected based on their biological and therapeutical relevance.

Comprehensive biomarker testing is recommended for adults with advanced cancer (stage III-IV) - with solid tumors, such as breast cancer, non-small-cell lung cancer, gastroesophageal cancer, pancreatic cancer and prostate cancer - or for children with glioblastoma. In case of carcinomas of unknown primary origin (CUP cancer), OncoDEEP® can help deciper the primary origin of the tumor and guide clinicians towards approved therapies or drugs currently in development in clinical trials.

OncoDEEP® can be used at diagnosis or at disease progression to identify biomarker-matched targeted therapies or biomarker-stratified clinical trials. It can also provide physicians with extra therapeutic guidance when first-line treatment does not work; when new biomarkers are required for second-line treatment; when recurrence occurs, or when patients are diagnosed with highly aggressive or rare cancers like a cancer of unknow primary.

OncoDEEP® can be performed on tissue biopsy, fine needle biopsy​ or bone marrow aspirate.​ The quality of laboratory test results is highly dependent on proper specimen collection and handling procedures. Our teams can guide you through our sample preparation protocol in case of any questions. All histologic samples will be reviewed by a pathologist after reception at OncoDNA.

The ISO 15189 (Medical laboratories-Requirements for quality and competence), CE-IVD (In vitro diagnostic devices complied to be sold in Europe), ISO 27001 (Information security management) and ISO 13485:2016 (Quality Management System) apply to our OncoDEEP® comprehensive biomarker test.

Ordering a solution is very simple: Just log in to OncoSHARE and select the solution(s) you are interested in. If you do not have a kit for sample collection, we will send you one.

You can order an OncoDEEP® from anywhere in the world. In the United States, OncoDEEP® can be used for academic projects only. The test cannot be used for molecular diagnostics yet.

After sample processing and data interpretation by our expert team, a comprehensive and interactive report will be made available for you on the OncoSHARE platform. It will help you select the most appropriate treatments based on the unique signature of your patient's tumor. You will also be able to share the report with your colleagues.

It takes about 10 working days from the sample quality control check to reporting.

For information regarding the price of our OncoDEEP® biomarker test in your respective country, please contact our sales team.

Cannot find what you are looking for? Contact us! Our Scientific Support Teams are available to answer all your questions from Monday to Friday.

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